Fuchs endothelial corneal dystrophy (FECD) is an age-related cause of vision loss. and the most common repeat expansion-mediated disease in humans characterised to date. Up to 80% of European FECD cases have been attributed to expansion of a non-coding CTG repeat element (termed CTG18. 1) located within the ubiquitously expressed transcription factor encoding gene. https://allfixelectricales.shop/product-category/motor-pulley/
Deciphering novel TCF4-driven mechanisms underlying a common triplet repeat expansion-mediated disease.
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