We present a small molecule pKa prediction tool entirely written in Python. It predicts the macroscopic pKa value and is trained on a literature compilation of monoprotic compounds. Different machine learning models were tested and random forest performed best given a five-fold cross-validation (mean absolute error=0. https://ashleyshomestores.shop/product-category/power-reclining-loveseat-with-console-adj-hdrst/