Purpose of the study: to present current data regarding challenges in treatment of castration-resistant prostate cancer (CRPC) and the relationship between CRPC and the expression of prostate-specific membrane antigen (psma). Material and Methods. The search for relevant sources was carried out in the Pubmed. elibrary. https://lecoureures.shop/product-category/course-a-pied-enfant-chaussures-stabilite/